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My Cart> Small Molecule Compounds > Anti-Infection > Anti-Bacterial > Proflavine HemisulfateCAS：1811-28-5
Molecular Formula：C13H11N3·1/2H2O4S
Molecular Weight：258.29
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1811-28-5 |
| Name | Proflavine Hemisulfate |
| Molecular Formula | C13H11N3·1/2H2O4S |
| Molecular Weight | 258.29 |
| Solubility | Soluble in Water(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 217-320-3 |
| MDL | MFCD00149650 |
| SMILES | C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N.C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N.OS(=O)(=O)O |
| InChIKey | YADYXCVYLIKQJX-UHFFFAOYSA-N |
| InChI | InChI=1S/2C13H11N3.H2O4S/c2*14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;1-5(2，3)4/h2*1-7H，14-15H2;(H2，1，2，3，4) |
| PubChem CID | 9849425 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | It is a DNA embedding agent that has antibacterial activity and can disrupt DNA synthesis by chelating with DNA. |
| Biological Activity | Proflavine Hemisulfate 是一种吖啶染料，是一种已知的DNA嵌入剂，抗微生物剂，可作为Kir3.2的孔隙阻滞剂，是治疗Kir3.2相关神经系统疾病的潜在先导化合物。[1-2] |
| Data Literature Source | [1]. Gatasheh M K ，et al.Proflavine an acridine DNA intercalating agent and strong antimicrobial possessing potential properties of carcinogen[J].Karbala International Journal of Modern Science，2017:S2405609X17301446. [2]. Kawada H，et al. Isolation of proflavine as a blocker of G protein-gated inward rectifier potassium channels by a cell growth-based screening system. Neuropharmacology. 2016 Oct;109:18-28. |
| Unit | Bottle |
| Specification | 25mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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