CAS:22204-24-6
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Light yellow to yellow Solid
array(6) { [0]=> array(7) { ["cat_id"]=> string(3) "123" ["cat_name"]=> string(14) "Anti-Infection" ["cat_desc"]=> string(0) "" ["child_id"]=> string(3) "369" ["child_name"]=> string(14) "Anti-Bacterial" ["child_desc"]=> string(0) "" ["sort_order"]=> string(1) "1" } [1]=> array(7) { ["cat_id"]=> string(3) "123" ["cat_name"]=> string(14) "Anti-Infection" ["cat_desc"]=> string(0) "" ["child_id"]=> string(3) "370" ["child_name"]=> string(11) "Anti-Fungal" ["child_desc"]=> string(0) "" ["sort_order"]=> string(1) "2" } [2]=> array(7) { ["cat_id"]=> string(3) "123" ["cat_name"]=> string(14) "Anti-Infection" ["cat_desc"]=> string(0) "" ["child_id"]=> string(3) "371" ["child_name"]=> string(13) "Anti-Parasite" ["child_desc"]=> string(0) "" ["sort_order"]=> string(1) "3" } [3]=> array(7) { ["cat_id"]=> string(3) "123" ["cat_name"]=> string(14) "Anti-Infection" ["cat_desc"]=> string(0) "" ["child_id"]=> string(3) "373" ["child_name"]=> string(10) "Antibiotic" ["child_desc"]=> string(0) "" ["sort_order"]=> string(1) "4" } [4]=> array(7) { ["cat_id"]=> string(3) "123" ["cat_name"]=> string(14) "Anti-Infection" ["cat_desc"]=> string(0) "" ["child_id"]=> string(3) "708" ["child_name"]=> string(9) "Antiviral" ["child_desc"]=> string(0) "" ["sort_order"]=> string(1) "5" } [5]=> array(7) { ["cat_id"]=> string(3) "123" ["cat_name"]=> string(14) "Anti-Infection" ["cat_desc"]=> string(0) "" ["child_id"]=> string(3) "376" ["child_name"]=> string(19) "Insecticide Related" ["child_desc"]=> string(0) "" ["sort_order"]=> string(1) "6" } } Array ( [123] => Array ( [id] => 123 [name] => Anti-Infection [num] => 0 ) )
CAS:22204-24-6
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Light yellow to yellow Solid
CAS | 22204-24-6 |
Chinese Name | 双羟萘酸噻嘧啶 |
English Name | Pyrantel Pamoate |
Synonyms | Pyrantelembonate;双羟乃酸噻嘧啶;Embovin; |
Molecular Formula | C34H30N2O6S |
Molecular Weight | 594.68 |
Solubility | Soluble in DMSO(Need ultrasonic) |
Purity | ≥98% |
Appearance | Light yellow to yellow Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
EC | EINECS 244-837-1 |
MDL | MFCD00072037 |
SMILES | CN1CCCN=C1C=CC2=CC=CS2.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O |
InChIKey | AQXXZDYPVDOQEE-MXDQRGINSA-N |
InChI | InChI=1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+ |
PubChem CID | 5281033 |
Target Point | Parasite;nAChR |
Passage | Anti-infection;Neuronal Signaling;Membrane Transporter&Ion Channel |
Background | It is an effective repellent compound and a nicotinic acetylcholine receptor (nAChR) agonist. |
Biological Activity | Pyrantel Pamoate 是一种口服活性抗蠕虫药,也是烟碱乙酰胆碱受体(nAChR)的激动剂,可导致寄生虫肌肉痉挛性麻痹。可用于研究蛔虫病、钩虫感染、肠道蠕虫(蛲虫感染)、旋毛虫病和毛滴虫病等寄生虫感染。[1-2] |
In Vivo | 双羟萘酸噻嘧啶(10 nM-10 μM;72 小时)显示出良好的抗鼠蚁活性,(0-168.2 M;72 小时)显示出良好的抗美洲疟原虫活性。双羟萘酸噻嘧啶(10 mg/kg;p.o. ;单次)可减少感染 A. ceylanicum 的仓鼠体内的蠕虫,蠕虫负担减少率为 87.2%,驱虫率为 63.4%[2]。 |
Data Literature Source | [1]. Martin RJ,et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. Int J Parasitol. 2004 Aug;34(9):1083-90. [2]. Tritten L,et al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS Negl Trop Dis. 2011 Dec;5(12):e1457. |
Unit | Bottle |
Specification | 50mg 100mg |