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My CartCAS：3424-98-4
Molecular Formula：C10H14N2O5
Molecular Weight：242.23
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 3424-98-4 |
| Name | Telbivudine |
| Molecular Formula | C10H14N2O5 |
| Molecular Weight | 242.23 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD02683612 |
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O |
| InChIKey | IQFYYKKMVGJFEH-CSMHCCOUSA-N |
| InChI | InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3，6-8，13-14H，2，4H2，1H3，(H，11，15，16)/t6-，7+，8+/m1/s1 |
| PubChem CID | 159269 |
| Target Point | HBV |
| Passage | Anti-infection |
| Background | Telbivudine is an HBV reverse transcriptase inhibitor that can be used in the study of hepatitis B infection. |
| Biological Activity | Telbivudine 是一种口服活性胸苷核苷类似物，是乙型肝炎病毒（HBV）复制的强效抗病毒抑制剂。[1] |
| Data Literature Source | [1]. Bridges EG，et al. Nonclinical safety profile of telbivudine，a novel potent antiviral agent for treatment of hepatitis B. Antimicrob Agents Chemother. 2008 Jul;52(7):2521-8. doi: 10.1128/AAC.00029-08. Epub 2008 May 12. [2]. Wu ZG，et al. Telbivudine preserves T-helper 1 cytokine production and downregulates programmed death ligand 1 in a mouse model of viral hepatitis. J Viral Hepat. 2010 Mar;17 Suppl 1(Suppl 1):24-33. [3]. Seifer M，et al. Telbivudine，a nucleoside analog inhibitor of HBV polymerase，has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir. Antiviral Res. 2009 Feb;81(2):147-55. |
| Unit | Bottle |
| Specification | 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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