{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Others > Tenofovir AlafenamideCAS：379270-37-8
Molecular Formula：C21H29N6O5P
Molecular Weight：476.47
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 379270-37-8 |
| Name | Tenofovir Alafenamide |
| Molecular Formula | C21H29N6O5P |
| Molecular Weight | 476.47 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD23843796 |
| SMILES | CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3 |
| InChIKey | LDEKQSIMHVQZJK-CAQYMETFSA-N |
| InChI | InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29，32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9，11-12，14-16H，10，13H2，1-4H3，(H，26，29)(H2，22，23，24)/t15-，16+，33+/m1/s1 |
| PubChem CID | 9574768 |
| Target Point | Others |
| Passage | Others |
| Background | Tenofovir alafenamide is a precursor compound to Tenofovir. |
| Biological Activity | Tenofovir Alafenamide 是一种tenofovir的前药，是一种 HIV-1 核苷酸逆转录酶抑制剂，可以用于治疗HIV和乙型肝炎。[1-2] |
| Data Literature Source | [1]. Babusis D，et al. Mechanism for effective lymphoid cell and tissue loading following oral administration of nucleotide prodrug GS-7340. Mol Pharm. 2013 Feb 4;10(2):459-66. [2]. Ruane PJ，et al. Antiviral activity，safety，and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults. J Acquir Immune Defic Syndr. 2013 Aug 1;63(4):449-55. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
