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My Cart> Small Molecule Compounds > Anti-Infection > Anti-Bacterial > Valnemulin HydrochlorideCAS：133868-46-9
Molecular Formula：C31H53ClN2O5S
Molecular Weight：601.28
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 133868-46-9 |
| Name | Valnemulin Hydrochloride |
| Molecular Formula | C31H53ClN2O5S |
| Molecular Weight | 601.28 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD08458958 |
| SMILES | C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CSC(C)(C)CNC(=O)[C@@H](C(C)C)N)C.Cl |
| InChIKey | MFBPRQKHDIVLOJ-AFFLPQGKSA-N |
| InChI | InChI=1S/C31H52N2O5S.ClH/c1-10-29(8)15-22(38-23(35)16-39-28(6，7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31;/h10，18-20，22，24-26，36H，1，11-17，32H2，2-9H3，(H，33，37);1H/t19-，20+，22-，24-，25+，26+，29-，30+，31+;/m1./s1 |
| PubChem CID | 60195218 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | It is an antibiotic that inhibits protein synthesis in bacteria by binding to peptidyl transferase in the 50s ribosome subunit. |
| Biological Activity | Valnemulin Hydrochloride 是一种胸腺嘧啶类抗生素，是肽基转移酶的强抑制剂，通过结合 50s 核糖体亚基中的肽基转移酶来抑制细菌的蛋白质合成。[1-3] |
| Data Literature Source | [1]. Poulsen SM，et al. The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome. Mol Microbiol. 2001 Sep;41(5):1091-9. [2]. Hannan PC，et al. In vitro susceptibilities of recent field isolates of Mycoplasma hyopneumoniae and Mycoplasma hyosynoviae to valnemulin (Econor)，tiamulin and enrofloxacin and the in vitro development of resistance to certain antimicrobial agents in Mycoplasma hyopneumoniae. Res Vet Sci. 1997 Sep-Oct;63(2):157-60. [3]. Chen Z，et al. Preventive effects of valnemulin on lipopolysaccharide-induced acute lung injury in mice. Inflammation. 2010 Oct;33(5):306-14. |
| Unit | Bottle |
| Specification | 10mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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