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My Cart> Small Molecule Compounds > Anti-Infection > Antiviral > Amantadine HydrochlorideCAS：665-66-7
Molecular Formula：C10H18ClN
Molecular Weight：187.71
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 665-66-7 |
| Name | Amantadine Hydrochloride |
| Molecular Formula | C10H18ClN |
| Molecular Weight | 187.71 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 211-560-2 |
| MDL | MFCD00074723 |
| SMILES | C1C2CC3CC1CC(C2)(C3)N.Cl |
| InChIKey | WOLHOYHSEKDWQH-UHFFFAOYSA-N |
| InChI | InChI=1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H，1-6，11H2;1H |
| PubChem CID | 64150 |
| Target Point | Influenza Virus |
| Passage | Anti-infection |
| Background | It is an effective antiviral compound against influenza A virus. It has an inhibitory effect on many ion channels, such as NMDA and M2, and also has anti-orthopoxvirus activity. |
| Biological Activity | Amantadine Hydrochloride 是一种口服高效抗病毒药，对甲型流感病毒具有活性。Amantadine Hydrochloride 可抑制多种离子通道，如 NMDA 和 M2，还可抑制冠状病毒离子通道。还具有抗逆转录病毒和抗癌活性。可用于帕金森病、术后认知功能障碍（POCD）和 COVID-19 研究。[1-4] |
| Data Literature Source | [1]. Suzuki H，et al. Emergence of amantadine-resistant influenza A viruses: epidemiological study. J Infect Chemother. 2003 Sep;9(3):195-200. [2]. Fink K，et al. Amantadine Inhibits SARS-CoV-2 In Vitro. Viruses. 2021 Mar 24;13(4):539. [3]. Zhang J，et al. Amantadine alleviates postoperative cognitive dysfunction possibly by increasing glial cell line-derived neurotrophic factor in rats. Anesthesiology. 2014 Oct;121(4):773-85. [4]. Lan Z，et al. Amantadine inhibits cellular proliferation and induces the apoptosis of hepatocellular cancer cells in vitro. Int J Mol Med. 2015 Sep;36(3):904-10. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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