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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > Betahistine DihydrochlorideCAS：5579-84-0
Molecular Formula：C8H14Cl2N2
Molecular Weight：209.12
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 5579-84-0 |
| Name | Betahistine Dihydrochloride |
| Molecular Formula | C8H14Cl2N2 |
| Molecular Weight | 209.12 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 226-966-5 |
| MDL | MFCD00012813 |
| SMILES | CNCCC1=CC=CC=N1.Cl.Cl |
| InChIKey | XVDFMHARQUBJRE-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4，6，9H，5，7H2，1H3;2*1H |
| PubChem CID | 68643 |
| Target Point | Histamine H3 Receptor |
| Passage | GPCR & G Protein;Neuronal Signaling;Immunology & Inflammation |
| Background | It is a histamine H3 receptor inhibitor. |
| Biological Activity | Betahistine Dihydrochloride 是一种口服活性组胺 H1 （histamine H1）受体激动剂和 H3 受体拮抗剂，可用于类风湿性关节炎（RA）的研究。[1-3] |
| Data Literature Source | [1]. Poyurovsky M，et al. The effect of betahistine，a histamine H1 receptor agonist/H3 antagonist，on olanzapine-induced weight gain in first-episode schizophrenia patients. Int Clin Psychopharmacol. 2005 Mar;20(2):101-3. [2]. Gbahou F，et al. Effects of betahistine at histamine H3 receptors: mixed inverse agonism/agonism in vitro and partial inverse agonism in vivo. J Pharmacol Exp Ther. 2010 Sep 1;334(3):945-54. [3]. Tang KT，et al. Betahistine attenuates murine collagen-induced arthritis by suppressing both inflammatory and Th17 cell responses. Int Immunopharmacol. 2016 Oct;39:236-245. |
| Unit | Bottle |
| Specification | 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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