{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > CarprofenCAS：53716-49-7
Molecular Formula：C15H12ClNO2
Molecular Weight：273.71
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 53716-49-7 |
| Name | Carprofen |
| Molecular Formula | C15H12ClNO2 |
| Molecular Weight | 273.71 |
| Solubility | Soluble in DMSO ≥3mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 258-712-4 |
| MDL | MFCD00079028 |
| SMILES | CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O |
| InChIKey | PUXBGTOOZJQSKH-UHFFFAOYSA-N |
| InChI | InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8，17H，1H3，(H，18，19) |
| PubChem CID | 2581 |
| Target Point | COX；FAAH |
| Passage | Immunology & Inflammation;Metabolic Enzyme&Protease |
| Background | It is a non-steroidal anti-inflammatory compound and a multi-target FAAH/COX inhibitor that can inhibit the activity of COX-2, COX-1 and FAAH. |
| Biological Activity | Carprofen 是一种非甾体抗炎药，是一种多靶点 FAAH/COX 抑制剂，对 COX-2、COX-1 和 FAAH 的 IC50 分别为 3.9 μM、22.3 μM 和 78.6 μM。[1] |
| IC50 | COX-1: 22.3μM(IC50);COX-2: 3.9μM(IC50);FAAH: 78.6μM(IC50)[1] |
| Data Literature Source | [1]. Favia AD，et al. Identification and characterization of carprofen as a multitarget fatty acid amide hydrolase/cyclooxygenase inhibitor. J Med Chem. 2012 Oct 25;55(20):8807-26. [2]. Waldherr K，et al. In vitro cytoprotective effects of acetylsalicylic acid，carprofen，meloxicam，or robenacoxib against apoptosis induced by sodium nitroprusside in canine cruciate ligament cells. Am J Vet Res. 2012 Nov;73(11):1752-8. [3]. Sessions JK，et al. In vivo effects of carprofen，deracoxib，and etodolac on prostanoid production in blood，gastric mucosa，and synovial fluid in dogs with chronic osteoarthritis. Am J Vet Res. 2005 May;66(5):812-7. |
| Unit | Bottle |
| Specification | 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
