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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > Chloropyramine HydrochlorideCAS：6170-42-9
Molecular Formula：C16H21Cl2N3
Molecular Weight：326.26
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 6170-42-9 |
| Name | Chloropyramine Hydrochloride |
| Molecular Formula | C16H21Cl2N3 |
| Molecular Weight | 326.26 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 228-216-2 |
| MDL | MFCD00079009 |
| SMILES | CN(C)CCN(CC1=CC=C(C=C1)Cl)C2=CC=CC=N2.Cl |
| InChIKey | VEYWWAGBHABATA-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H20ClN3.ClH/c1-19(2)11-12-20(16-5-3-4-10-18-16)13-14-6-8-15(17)9-7-14;/h3-10H，11-13H2，1-2H3;1H |
| PubChem CID | 80311 |
| Target Point | Histamine H1 Receptor;FAK;VEGFR |
| Passage | GPCR & G Protein;Neuronal Signaling;Immunology & Inflammation;Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | It is a histamine receptor H1 antagonist and can also inhibit the activity of VEGFR-3 and FAK. |
| Biological Activity | Chloropyramine Hydrochloride 是一种组胺受体 H1 (histamine receptor H1) 拮抗剂，也能抑制 VEGFR-3 和 FAK 的生化功能。[1] |
| Data Literature Source | [1]. Kurenova EV，et al. Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo. J Med Chem. 2009 Aug 13;52(15):4716-24. |
| Unit | Bottle |
| Specification | 25mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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