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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Mefenamic AcidCAS：61-68-7
Molecular Formula：C15H15NO2
Molecular Weight：241.29
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 61-68-7 |
| Name | Mefenamic Acid |
| Molecular Formula | C15H15NO2 |
| Molecular Weight | 241.29 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-513-1 |
| MDL | MFCD00051721 |
| SMILES | CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C |
| InChIKey | HYYBABOKPJLUIN-UHFFFAOYSA-N |
| InChI | InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9，16H，1-2H3，(H，17，18) |
| PubChem CID | 4044 |
| Target Point | COX |
| Passage | Immunology & Inflammation |
| Background | It is a non-steroidal anti-inflammatory compound and a competitive hCOX-1 and hCOX-2 inhibitor. |
| Biological Activity | Mefenamic Acid 是一种非甾体抗炎药，是 hCOX-1 和 hCOX-2 的竞争性抑制剂，对 hCOX-1 和 hCOX-2 的 IC50 值分别为 40 nM 和 3 μM。[1-2] |
| IC50 | hCOX-1: 40nM(IC50);hCOX-2: 3μM(IC50)[1] |
| Data Literature Source | [1]. Gierse JK，et al. Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase. Biochem J. 1995 Jan 15;305 ( Pt 2)(Pt 2):479-84. [2]. Hashemipour MA，et al. In Vitro Cytotoxic Effects of Celecoxib，Mefenamic Acid，Aspirin and Indometacin on Several Cells Lines. J Dent (Shiraz). 2016 Sep;17(3):219-25. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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