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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > MRS-2578CAS：711019-86-2
Molecular Formula：C20H20N6S4
Molecular Weight：472.67
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 711019-86-2 |
| Name | MRS-2578 |
| Molecular Formula | C20H20N6S4 |
| Molecular Weight | 472.67 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD07370141 |
| SMILES | C1=CC(=CC(=C1)N=C=S)NC(=S)NCCCCNC(=S)NC2=CC(=CC=C2)N=C=S |
| InChIKey | QOHNRGHTJPFMSL-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H20N6S4/c27-13-23-15-5-3-7-17(11-15)25-19(29)21-9-1-2-10-22-20(30)26-18-8-4-6-16(12-18)24-14-28/h3-8，11-12H，1-2，9-10H2，(H2，21，25，29)(H2，22，26，30) |
| PubChem CID | 16078986 |
| Target Point | P2Y Receptor |
| Passage | GPCR & G Protein |
| Background | MRS 2578 is an effective P2Y6 receptor inhibitor with weak action on P2Y1, P2Y2, P2Y4 and P2Y11 receptors. |
| Biological Activity | MRS-2578 是一种选择性强效 P2Y6 受体拮抗剂，IC50 为 37 nM（人）和 98 nM（大鼠），对 P2Y1、P2Y2、P2Y4 和 P2Y11 受体的活性不显著。[1-2] |
| Data Literature Source | [1]. Mamedova LK，et al. Diisothiocyanate derivatives as potent，insurmountable antagonists of P2Y6 nucleotide receptors. Biochem Pharmacol. 2004 May 1;67(9):1763-70. [2]. Vieira RP，et al. Purinergic receptor type 6 contributes to airway inflammation and remodeling in experimental allergic airway inflammation. Am J Respir Crit Care Med. 2011 Jul 15;184(2):215-23. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
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