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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > NabumetoneCAS：42924-53-8
Molecular Formula：C15H16O2
Molecular Weight：228.29
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 42924-53-8 |
| Name | Nabumetone |
| Molecular Formula | C15H16O2 |
| Molecular Weight | 228.29 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 611-790-7 |
| MDL | MFCD00079518 |
| SMILES | CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC |
| InChIKey | BLXXJMDCKKHMKV-UHFFFAOYSA-N |
| InChI | InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H，3-4H2，1-2H3 |
| PubChem CID | 4409 |
| Target Point | COX-2 |
| Passage | Immunology & Inflammation |
| Background | Nabumetone is a non-acid anti-inflammatory compound and a potent and selective COX-2 inhibitor. |
| Biological Activity | Nabumetone 是一种口服活性非酸性消炎药，是一种强效的选择性 COX-2 抑制剂，也是活性代谢物 6MNA 的原药。[1-2] |
| Data Literature Source | [1]. Vural F，et al. Cyclo-oxygenase 2 inhibitor，nabumetone，inhibits proliferation in chronic myeloid leukemia cell lines. Leuk Lymphoma. 2005 May;46(5):753-6. [2]. Melarange R，et al. Anti-inflammatory and gastrointestinal effects of nabumetone or its active metabolite，6MNA (6-methoxy-2-naphthylacetic acid): comparison with indomethacin. Agents Actions. 1992;Spec No:C82-3. |
| Unit | Bottle |
| Specification | 250mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
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