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My CartCAS：522-48-5
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 522-48-5 |
| Name | Tetrahydrozoline Hydrochloride |
| Molecular Formula | C13H17ClN2 |
| Molecular Weight | 236.74 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-329-3 |
| MDL | MFCD00058029 |
| SMILES | C1CC(C2=CC=CC=C2C1)C3=NCCN3.Cl |
| InChIKey | BJORNXNYWNIWEY-UHFFFAOYSA-N |
| InChI | InChI=1S/C13H16N2.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13;/h1-2，4，6，12H，3，5，7-9H2，(H，14，15);1H |
| PubChem CID | 10648 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein；Neuronal Signaling |
| Background | It is an alpha-adrenergic receptor agonist. |
| Biological Activity | Tetrahydrozoline Hydrochloride 是咪唑啉的衍生物，是一种能引起血管收缩的α-肾上腺素能激动剂。盐酸四氢唑啉被广泛用于治疗鼻塞和结膜充血。[1-2] |
| In Vitro | 盐酸四氢唑啉(0.05%；24 小时)可诱导原代人牙龈成纤维细胞合成 I 型和 III 型胶原蛋白[2]。 |
| In Vivo | 盐酸四氢唑啉大剂量使用会导致中毒，表现为低血压、心动过速和中枢神经系统抑制[1]。 |
| Data Literature Source | [1]. Peat J，et al. Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS). Methods Mol Biol. 2010;603:501-8. [2]. Nowakowska D，et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar;19(3):2037-2044. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
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