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My CartCAS：59-97-2
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
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| CAS | 59-97-2 |
| Name | Tolazoline Hydrochloride |
| Molecular Formula | C10H13ClN2 |
| Molecular Weight | 196.68 |
| Solubility | Soluble in Water/DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-447-3 |
| MDL | MFCD00012693 |
| SMILES | C1CN=C(N1)CC2=CC=CC=C2.Cl |
| InChIKey | RHTNTTODYGNRSP-UHFFFAOYSA-N |
| InChI | InChI=1S/C10H12N2.ClH/c1-2-4-9(5-3-1)8-10-11-6-7-12-10;/h1-5H，6-8H2，(H，11，12);1H |
| PubChem CID | 6048 |
| Target Point | Adrenergic Receptor |
| Passage | Endocrinology & Hormones;GPCR & G Protein；Neuronal Signaling |
| Background | It is a non-selective and competitive alpha-adrenergic receptor antagonist. |
| Biological Activity | Tolazoline Hydrochloride 是一种非选择性竞争性α-肾上腺素能受体拮抗剂。[1-2] |
| In Vitro | Tolazoline(4 x 10(-6)M)for 30 minutes is not as broadly effective as SNP against all spasmogens investigated; however，it may be effective in counteracting alpha-adrenoceptor-mediated vasospasm in human radial arteries. |
| Data Literature Source | [1]. Teskin O，et al. Comparative effects of tolazoline and nitroprusside on human isolated radial artery. Ann Thorac Surg. 2006 Jan;81(1):125-31. [2]. Lei L，et al. Activation of L-type calcium channel by tolazoline derivatives: role of isothiocyanate moiety. J Cardiovasc Pharmacol. 1998 May;31(5):721-33. |
| Unit | Bottle |
| Specification | 500mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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