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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > Mepazine HydrochlorideCAS：2975-36-2
Molecular Formula：C20H11F6N5O2
Molecular Weight：346.92
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 2975-36-2 |
| Name | Mepazine Hydrochloride |
| Molecular Formula | C20H11F6N5O2 |
| Molecular Weight | 346.92 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CN1CCCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42.Cl |
| InChIKey | RLCFKYRNUBRPIK-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H22N2S.ClH/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21;/h2-5，8-11，15H，6-7，12-14H2，1H3;1H |
| PubChem CID | 102907 |
| Target Point | MALT1 |
| Passage | Metabolic Enzyme&Protease |
| Background | It is an effective selective inhibitor of MALT1 protease. |
| Biological Activity | Mepazine Hydrochloride 是一种有效的选择性 MALT1 蛋白酶抑制剂，抑制全长 GSTMALT1 和 GSTMALT1 325-760 段的IC50 分别为 0.83 和 0.42 μM。[1] |
| Data Literature Source | [1]. Nagel D，et al. Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL. Cancer Cell. 2012 Dec 11;22(6):825-37. |
| Unit | Bottle |
| Specification | 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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