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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > MLT-748CAS：1832578-30-9
Molecular Formula：C19H16ClN5OS
Molecular Weight：492.32
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1832578-30-9 |
| Name | MLT-748 |
| Molecular Formula | C19H16ClN5OS |
| Molecular Weight | 492.32 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC(C(C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=C(N=C3)N4N=CC=N4)Cl)OC)OC |
| InChIKey | XKQLNDPUQSZBJW-QGHHPUGFSA-N |
| InChI | InChI=1S/C19H19Cl2N9O3/c1-10(32-2)17(33-3)16-13(9-22-15-7-14(21)28-29(15)16)27-19(31)26-11-6-12(20)18(23-8-11)30-24-4-5-25-30/h4-10，17H，1-3H3，(H2，26，27，31)/t10-，17+/m1/s1 |
| PubChem CID | 129072285 |
| Target Point | MALT1 |
| Passage | Metabolic Enzyme&Protease |
| Background | MLT-748 is a potent and selective isomorphic inhibitor of MALT1. |
| Biological Activity | MLT-748 是 MALT1 的一种强效、选择性和异构抑制剂，能在异构 Trp580 口袋中与 MALT1 结合，IC50 为 5 nM。[1] |
| IC50 | MALT1: 5nM(IC50)[1] |
| Data Literature Source | [1]. Quancard J，et al. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat Chem Biol. 2019 Mar;15(3):304-313. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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