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Velutin

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Cat.No：IV0970 Solarbio

CAS：25739-41-7

Molecular Formula：C₁₇H₁₄O₆

Molecular Weight：314.29

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：White to yellow Solid

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Product Information

CAS	25739-41-7
Name	Velutin
Molecular Formula	C₁₇H₁₄O₆
Molecular Weight	314.29
Solubility	Soluble in DMSO
Purity	HPLC≥98%
Appearance	White to yellow Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
MDL	MFCD20260863
SMILES	COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)OC)O
InChIKey	ROCUOVBWAWAQFD-UHFFFAOYSA-N
InChI	InChI=1S/C17H14O6/c1-21-10-6-12(19)17-13(20)8-14(23-16(17)7-10)9-3-4-11(18)15(5-9)22-2/h3-8，18-19H，1-2H3
PubChem CID	5464381
Target Point	Osteoclast;HIF-1α
Passage	Immunology & Inflammation;HIF
Background	Velutin can reduce osteoclast differentiation and down-regulate HIF-1α through NF-κB pathway, and has the activity of inhibiting melanin biosynthesis.
Biological Activity	Velutin 是从Flammulina velutipes中提取的一种苷元，抑制黑色素生物合成。Velutin 可减少破骨细胞分化并下调 HIF-1α。[1-2]
Data Literature Source	[1]. Jung SH，et al. Velutin，an Aglycone Extracted from Korean Mistletoe，with Improved Inhibitory Activity against Melanin Biosynthesis. Molecules. 2019 Jul 12;24(14):2549. [2]. Brito C，et al. Cytotoxicity and potential anti-inflammatory activity of velutin on RAW 264.7 cell line differentiation: Implications in periodontal bone loss. Arch Oral Biol. 2017 Nov;83:348-356.
Unit	Bottle
Specification	5mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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