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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Risedronic acidCAS：105462-24-6
Molecular Formula：C7H11NO7P2
Molecular Weight：283.11
Storage：Powder:2-8℃，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 105462-24-6 |
| Name | Risedronic acid |
| Molecular Formula | C7H11NO7P2 |
| Molecular Weight | 283.11 |
| Solubility | Soluble in Water/DMSO ＜ 1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years |
| MDL | MFCD00867080 |
| SMILES | C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)O |
| InChIKey | IIDJRNMFWXDHID-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H11NO7P2/c9-7(16(10，11)12，17(13，14)15)4-6-2-1-3-8-5-6/h1-3，5，9H，4H2，(H2，10，11，12)(H2，13，14，15) |
| PubChem CID | 5245 |
| Target Point | Osteoclast |
| Passage | Immunology & Inflammation |
| Background | Risedronate is the latest (III) generation of bisphosphonates， the most efficient anti-resorption drugs that inhibit osteoclast-mediated bone resorption and change the bone metabolism. The antimalarial activities of risedronate， one of the most potent bisphosphonates clinically used to treat bone resorption diseases， against blood stages of Plasmodium falciparum (50% inhibitory concentration [IC50] of 20.3±1.0 μM).[1-2] |
| Biological Activity | Risedronic acid 是一种吡啶基双膦酸盐，可抑制破骨细胞介导的骨吸收。[1-2] |
| Data Literature Source | [1]. Giljevi Z，et alTreatment of osteoporosis by risedronate-- speed，efficacy and safety. Reumatizam. 2006;53(2):66-71. [2]. Jord o FM，et al. In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum. Antimicrob Agents Chemother. 2011 May;55(5):2026-31. |
| Unit | Bottle |
| Specification | 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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