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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Alendronic acidCAS：66376-36-1
Molecular Formula：C4H13NO7P2
Molecular Weight：249.1
Storage：Powder:2-8℃，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 66376-36-1 |
| Name | Alendronic acid |
| Molecular Formula | C4H13NO7P2 |
| Molecular Weight | 249.1 |
| Solubility | Soluble in Water ≥0.1mg/mL(Need ultrasonic or Water bath) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years |
| EC | EINECS 204-352-8 |
| MDL | MFCD00868112 |
| SMILES | C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN |
| InChIKey | OGSPWJRAVKPPFI-UHFFFAOYSA-N |
| InChI | InChI=1S/C4H13NO7P2/c5-3-1-2-4(6，13(7，8)9)14(10，11)12/h6H，1-3，5H2，(H2，7，8，9)(H2，10，11，12) |
| PubChem CID | 2088 |
| Target Point | Osteoclast;FDPS |
| Passage | Immunology & Inflammation;Metabolic Enzyme&Protease |
| Background | Alendronic acid is an inhibitor of farnesyl diphosphate synthase (FDPS). Alendronic acid inhibits osteoclaster-mediated bone resorption. |
| Biological Activity | Alendronic acid 是一种双膦酸盐，是一种 FDPS 抑制剂。Alendronic acid 可抑制破骨细胞介导的骨吸收，用于治疗绝经后骨质疏松症。[1-2] |
| Data Literature Source | [1]. Teixeira S，et al. Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma. Pharmaceutics. 2020 Mar 24;12(3):293. [2]. Duckworth AD，et al. Effect of Alendronic Acid on Fracture Healing: A Multicenter Randomized Placebo-Controlled Trial. J Bone Miner Res. 2019 Jun;34(6):1025-1032. |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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