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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > Clodronic acid disodium saltCAS：22560-50-5
Molecular Formula：CH2Cl2Na2O6P2
Molecular Weight：288.86
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 22560-50-5 |
| Name | Clodronic acid disodium salt |
| Molecular Formula | CH2Cl2Na2O6P2 |
| Molecular Weight | 288.86 |
| Solubility | Soluble in Water |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 245-078-9 |
| MDL | MFCD01632786 |
| SMILES | C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.[Na+].[Na+] |
| InChIKey | HJKBJIYDJLVSAO-UHFFFAOYSA-L |
| InChI | InChI=1S/CH4Cl2O6P2.2Na/c2-1(3，10(4，5)6)11(7，8)9;;/h(H2，4，5，6)(H2，7，8，9);;/q;2*+1/p-2 |
| PubChem CID | 31195 |
| Target Point | Osteoclast |
| Passage | Immunology & Inflammation |
| Background | It is an inhibitor of osteoclastic bone resorption. |
| Biological Activity | Clodronic acid disodium salt 是第一代双膦酸盐，是一种口服活性破骨细胞骨吸收抑制剂。[1-3] |
| Data Literature Source | [1]. M nkk nen J，et al. Clodronate (dichloromethylene bisphosphonate) inhibits LPS-stimulated IL-6 and TNF production by RAW 264 cells. Life Sci. 1994;54(14):PL229-34. [2]. Tanakol R，et al. Clodronic acid in the treatment of postmenopausal osteoporosis. Clin Drug Investig. 2007;27(6):419-33. [3]. Itoh F，et al. Effects of clodronate and alendronate on local and systemic changes in bone metabolism in rats with adjuvant arthritis. Inflammation. 2004 Feb;28(1):15-21. |
| Unit | Bottle |
| Specification | 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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