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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > NDMC101CAS：1308631-40-4
Molecular Formula：C13H9ClFNO2
Molecular Weight：265.67
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1308631-40-4 |
| Name | NDMC101 |
| Molecular Formula | C13H9ClFNO2 |
| Molecular Weight | 265.67 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD13200880 |
| SMILES | C1=CC=C(C(=C1)C(=O)NC2=C(C=C(C=C2)Cl)F)O |
| InChIKey | NUQWCDAXACRITO-UHFFFAOYSA-N |
| InChI | InChI=1S/C13H9ClFNO2/c14-8-5-6-11(10(15)7-8)16-13(18)9-3-1-2-4-12(9)17/h1-7，17H，(H，16，18) |
| PubChem CID | 60202556 |
| Target Point | Osteoclast |
| Passage | Immunology & Inflammation |
| Background | NDMC101 is an effective osteoclast genesis inhibitor, which can inhibit osteoclast differentiation by down-regulating the expression of NFATc1 regulatory gene. NDMC101 can be used in the study of bone diseases, such as rheumatoid arthritis, synovitis, etc. |
| Biological Activity | NDMC101 是一种破骨细胞形成抑制剂，可通过下调 NFATc1 调控基因的表达来抑制破骨细胞分化。NDMC101 可用于研究类风湿性关节炎等骨科疾病以及滑膜炎症等。[1] |
| Data Literature Source | [1]. Cheng CP，et al. A benzamide-linked small molecule NDMC101 inhibits NFATc1 and NF-κB activity: a potential osteoclastogenesis inhibitor for experimental arthritis. J Clin Immunol. 2012 Aug;32(4):762-77. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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