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My CartCAS：64009-84-3
Molecular Formula：C19H17Cl2FN2O
Molecular Weight：379.26
Storage：Store at -20℃，2 years
Purity：≥98%
Appearance：Colorless to light yellow Oil
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| CAS | 64009-84-3 |
| Name | IMB-301 |
| Molecular Formula | C19H17Cl2FN2O |
| Molecular Weight | 379.26 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Colorless to light yellow Oil |
| Storage | Store at -20℃，2 years |
| SMILES | C1=CC(=CC=C1OCCC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)F |
| InChIKey | FHKXBOJPHOEMQO-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H17Cl2FN2O/c20-15-1-6-18(19(21)11-15)14(12-24-9-8-23-13-24)7-10-25-17-4-2-16(22)3-5-17/h1-6，8-9，11，13-14H，7，10，12H2 |
| PubChem CID | 327197 |
| Target Point | HIV(Vif) |
| Passage | Anti-infection |
| Background | IMB-301 is a specific HIV-1 replication inhibitor, which can bind to hA3G (human APOBEC3G), block the interaction of HA3G-VIF and inhibit the degradation of hA3G mediated by Vif. |
| Biological Activity | IMB-301 是一种特异性 HIV-1 复制抑制剂，能与 hA3G 结合，中断 hA3G-Vif 的相互作用，并抑制 Vif 介导的 hA3G 降解。[1] |
| Data Literature Source | [1]. Ma L，et al. Identification of small molecule compounds targeting the interaction of HIV-1 Vif and human APOBEC3G by virtual screening and biological evaluation. Sci Rep. 2018 May 23;8(1):8067. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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