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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Immunology & Inflammation > TLR7 agonist 2CAS：1642857-69-9
Molecular Formula：C17H16N6O2
Molecular Weight：336.35
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1642857-69-9 |
| Name | TLR7 agonist 2 |
| Molecular Formula | C17H16N6O2 |
| Molecular Weight | 336.35 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC1=CC(=NO1)COC2=NC(=NC3=C2N(C=C3)CC4=CC=CC=N4)N |
| InChIKey | FVKOYFLAKSGBBV-UHFFFAOYSA-N |
| InChI | InChI=1S/C17H16N6O2/c1-11-8-13(22-25-11)10-24-16-15-14(20-17(18)21-16)5-7-23(15)9-12-4-2-3-6-19-12/h2-8H，9-10H2，1H3，(H2，18，20，21) |
| PubChem CID | 86346192 |
| Target Point | TLR7 |
| Passage | Immunology & Inflammation |
| Background | TLR7 agonist 2 is an effective and selective toll-like receptor 7 (TLR7) agonist. |
| Biological Activity | TLR7 agonist 2 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM.[1] |
| IC50 | LEC: 0.4 μM (TLR7)[1] |
| Data Literature Source | [1]. McGowan DC， et al. Identification and Optimization of Pyrrolo[3，2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B. J Med Chem. 2017 Jul 27;60(14):6137-6151. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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