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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > NSC 23766CAS：733767-34-5
Molecular Formula：C24H35N7
Molecular Weight：421.58
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 733767-34-5 |
| Name | NSC 23766 |
| Molecular Formula | C24H35N7 |
| Molecular Weight | 421.58 |
| Solubility | Soluble in Water/DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C |
| InChIKey | DEFBCZWQLILOJF-UHFFFAOYSA-N |
| InChI | InChI=1S/C24H35N7/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22/h10-11，13-16H，6-9，12H2，1-5H3，(H2，25，26)(H2，27，28，29，30) |
| PubChem CID | 409805 |
| Target Point | Rac GTPase |
| Passage | Cell Cycle |
| Background | NSC 23766 is a specific Rac GTPase inhibitor for permeable cells. |
| Biological Activity | NSC 23766 is a cell-permeable， reversible and specific inhibitor of Rac GTPase， used for cancer treatment[1-4]. |
| Data Literature Source | [1]. Veluthakal R，et al. NSC23766，a Known Inhibitor of Tiam1-Rac1 Signaling Module，Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model. Cell Physiol Biochem. 2016;39(2):760-7. [2]. Song SJ，et al. Inhibition of Rac1 GTPase activity affects porcine oocyte maturation and early embryo development. Sci Rep. 2016 Oct 3;6:34415 [3]. Zhao L，et al. Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1，GDF9 and BMP15 transcription in mice. Sci Rep. 2016 Apr 6;6:23972 [4]. Wang Y，et al. Involvement of Rac1 signalling pathway in the development and maintenance of acute inflammatory pain induced by bee venom injection. Br J Pharmacol. 2016 Mar;173(5):937-50 |
| Unit | Bottle |
| Specification | 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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