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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > Sappanone ACAS：102067-84-5
Molecular Formula：C16H12O5
Molecular Weight：284.3
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Solid
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| CAS | 102067-84-5 |
| Name | Sappanone A |
| Molecular Formula | C16H12O5 |
| Molecular Weight | 284.3 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | HPLC≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | C1C(=CC2=CC(=C(C=C2)O)O)C(=O)C3=C(O1)C=C(C=C3)O |
| InChIKey | KVYZXXBTJHJISR-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H12O5/c17-11-2-3-12-15(7-11)21-8-10(16(12)20)5-9-1-4-13(18)14(19)6-9/h1-7，17-19H，8H2 |
| PubChem CID | 85044918 |
| Target Point | NF-κB;Nrf2 |
| Passage | NF-κB |
| Background | Sappanone A is a high isoflavone, which regulates Nrf2 and NF- κ B shows anti-inflammatory activity. |
| Biological Activity | Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma[1]. |
| Data Literature Source | [1]. Lee S，et，al. Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Int Immunopharmacol. 2015 Sep;28(1):328-36. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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