English Name |
Anti-SLC7A11/xCT Polyclonal Antibody |
Chinese Name |
钙离子通道阻端耐药蛋白CCBR1抗体 |
Target |
SLC7A11/xCT |
Synonym |
Amino acid transport system xc xCT antibody, Amino acid transport system xc- antibody Calcium channel blocker resistance protein CCBR1, Calcium channel blocker resistance protein CCBR1 antibody, CCBR1, Cysteine/glutamate transporter antibody, cystine/glutamate transporter, SLC7A11, Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11, solute carrier family 7, Solute carrier family 7 member 11, Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11, xCT, XCT_HUMAN |
Backgroud |
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. |
Swiss Prot |
Q9UPY5 |
Gene ID |
23657 |
Subcellular Localization |
Membrane,Multi-pass membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
55kDa |
Dilution Ratio |
WB 1:1000-5000. |
Immunogen |
A synthetic peptide of human SLC7A11/xCT |
Public Immunogen Range |
1-100aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Mouse Rat |
Application |
WB |
Specification |
50ul 100ul |