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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Protein Tyrosine Kinase/PTK > BAY-826CAS：1448316-08-2
Molecular Formula：C26H19F5N6OS
Molecular Weight：558.53
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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| CAS | 1448316-08-2 |
| Name | BAY-826 |
| Molecular Formula | C26H19F5N6OS |
| Molecular Weight | 558.53 |
| Solubility | Soluble in DMSO(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC1=CC(=C(C=C1NC(=O)C2=CC(=CC(=C2)C#N)S(F)(F)(F)(F)F)N3C=CN4C3=CC(=N4)C5=CN=CC=C5)C |
| InChIKey | MPASHPJAIUOWCK-UHFFFAOYSA-N |
| InChI | InChI=1S/C26H19F5N6OS/c1-16-8-17(2)24(36-6-7-37-25(36)13-23(35-37)19-4-3-5-33-15-19)12-22(16)34-26(38)20-9-18(14-32)10-21(11-20)39(27，28，29，30)31/h3-13，15H，1-2H3，(H，34，38) |
| PubChem CID | 71623052 |
| Target Point | TIE-2 |
| Passage | Protein Tyrosine Kinase/RTK |
| Background | BAY-826 is a selective and effective TIE-2 inhibitor. |
| Biological Activity | BAY-826 is a selective and potent TIE-2 inhibitor with a Kd of 1.6 nM， respectively.[1] |
| Data Literature Source | [1]. Schneider H， et al. J Neurochem. 2017 Jan; 140(1):170-182. doi: 10.1111/jnc.13877. Epub 2016 Dec 12.Novel TIE-2 inhibitor BAY-826 displays in vivo efficacy in experimental syngeneic murine glioma models. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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