PF-04691502
Cat.No:IP2280 Solarbio
CAS:1013101-36-4
Molecular Formula:C22H27N5O4
Molecular Weight:425.48
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Solid
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Small Molecule Compounds >
Inhibitors & Antagonists & Agonists >
PI3K/Akt/mTOR >
PF-04691502CAS:1013101-36-4
Molecular Formula:C22H27N5O4
Molecular Weight:425.48
Storage:Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year
Purity:≥98%
Appearance:Solid
Qty:
Size:
CAS | 1013101-36-4 |
Name | PF-04691502 |
Molecular Formula | C22H27N5O4 |
Molecular Weight | 425.48 |
Solubility | Soluble in DMSO |
Purity | ≥98% |
Appearance | Solid |
Storage | Powder:2-8℃,2 years;Insolvent(Mother Liquid):-20℃,6 months;-80℃,1 year |
MDL | MFCD18782794 |
SMILES | CC1=C2C=C(C(=O)N(C2=NC(=N1)N)C3CCC(CC3)OCCO)C4=CN=C(C=C4)OC |
InChIKey | XDLYKKIQACFMJG-UHFFFAOYSA-N |
InChI | InChI=1S/C22H27N5O4/c1-13-17-11-18(14-3-8-19(30-2)24-12-14)21(29)27(20(17)26-22(23)25-13)15-4-6-16(7-5-15)31-10-9-28/h3,8,11-12,15-16,28H,4-7,9-10H2,1-2H3,(H2,23,25,26) |
PubChem CID | 25033539 |
Target Point | PI3K; mTOR |
Passage | PI3K/Akt/mTOR |
Background | PF-04691502 is an effective and selective inhibitor of PI3K and mTOR. |
Biological Activity | PF-04691502 is a potent and selective inhibitor of PI3K and mTOR. PF-04691502 binds to human PI3Kα, β, δ, γ and mTOR with Kis of 1.8, 2.1, 1.6, 1.9 and 16 nM, respectively.[1] |
Data Literature Source | [1]. Yuan J,et al. PF-04691502,a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activity. Mol Cancer Ther. 2011 Nov;10(11):2189-99. |
Unit | Bottle |
Specification | 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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