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(Rac)-PF-998425

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Cat.No：IP6950 Solarbio

CAS：1076225-26-7

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：Solid

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Product Information

CAS	1076225-26-7
Name	(Rac)-PF-998425
Molecular Formula	C₁₄H₁₄F₃NO
Molecular Weight	269.26
Solubility	Soluble in DMSO
Purity	≥98%
Appearance	Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
SMILES	C1CCC(C(C1)C2=CC(=C(C=C2)C#N)C(F)(F)F)O
InChIKey	MENRRRXHFQYXDW-UHFFFAOYSA-N
InChI	InChI=1S/C14H14F3NO/c15-14(16，17)12-7-9(5-6-10(12)8-18)11-3-1-2-4-13(11)19/h5-7，11，13，19H，1-4H2
PubChem CID	25093229
Target Point	Androgen Receptor
Passage	Endocrinology & Hormones
Background	(Rac)-PF-998425 is an effective and selective nonsteroidal androgen receptor (AR) antagonist.
Biological Activity	(Rac)-PF-998425 is a potent， selective， nonsteroidal androgen receptor (AR) antagonist. (Rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays， respectively. (Rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
Data Literature Source	[1]. Li JJ，et al. Rational design and synthesis of 4-((1R，2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425)，a novel，nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7
Unit	Bottle
Specification	5mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.

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