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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > Afuresertib hydrochlorideCAS：1047645-82-8
Molecular Formula：C18H18Cl3FN4OS
Molecular Weight：463.78
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Yellow to brown Solid
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| CAS | 1047645-82-8 |
| Name | Afuresertib hydrochloride |
| Molecular Formula | C18H18Cl3FN4OS |
| Molecular Weight | 463.78 |
| Solubility | Soluble in DMSO ≥10mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Yellow to brown Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28167824 |
| SMILES | CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)N[C@@H](CC3=CC(=CC=C3)F)CN)Cl.Cl |
| InChIKey | YFQJOPFTGMHYNV-YDALLXLXSA-N |
| InChI | InChI=1S/C18H17Cl2FN4OS.ClH/c1-25-16(14(19)9-23-25)13-7-15(27-17(13)20)18(26)24-12(8-22)6-10-3-2-4-11(21)5-10;/h2-5，7，9，12H，6，8，22H2，1H3，(H，24，26);1H/t12-;/m0./s1 |
| PubChem CID | 46843056 |
| Target Point | Akt |
| Passage | PI3K/Akt/mTOR |
| Background | Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable， selective， ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively[1-2]. |
| Unit | Bottle |
| Specification | 2mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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