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1-Dodecylimidazole

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Cat.No：ID4380 Solarbio

CAS：4303-67-7

Molecular Formula：C₁₅H₂₈N₂

Molecular Weight：236.4

Storage：Store at 2-8℃，2 years

Purity：≥98%

Appearance：Liquid

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Product Information

CAS	4303-67-7
Name	1-Dodecylimidazole
Molecular Formula	C₁₅H₂₈N₂
Molecular Weight	236.4
Solubility	Soluble in DMSO(Need ultrasonic)
Purity	≥98%
Appearance	Liquid
Storage	Store at 2-8℃，2 years
MDL	MFCD00278859
SMILES	CCCCCCCCCCCCN1C=CN=C1
InChIKey	JMTFLSQHQSFNTE-UHFFFAOYSA-N
InChI	InChI=1S/C15H28N2/c1-2-3-4-5-6-7-8-9-10-11-13-17-14-12-16-15-17/h12，14-15H，2-11，13H2，1H3
PubChem CID	78002
Target Point	Others
Passage	Others
Background	1-Dodecylimidazole is a lysosome active detergent and cytotoxic compound.
Biological Activity	1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes， disruption of the lysosomal membrane， and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity[1-3].
Data Literature Source	[1]. Wilson PD，et al. A relationship between multidrug resistance and growth-state dependent cytotoxicity of the lysosomotropic detergent N-dodecylimidazole. Biochem Biophys Res Commun. 1991;176(3):1377-1382. [2]. Atkin SD，et al. The isolation of 2，3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole，a novel hypocholesterolaemic agent. Biochem J. 1972;130(1):153-157. [3]. Firestone RA，et al. Lysosomotropic agents. 7. Broad-spectrum antifungal activity of lysosomotropic detergents. J Med Chem. 1987;30(8):1519-1521.
Unit	Bottle
Specification	100mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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