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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > Defactinib hydrochlorideCAS：1073160-26-5
Molecular Formula：C20H22ClF3N8O3S
Molecular Weight：546.95
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1073160-26-5 |
| Name | Defactinib hydrochloride |
| Molecular Formula | C20H22ClF3N8O3S |
| Molecular Weight | 546.95 |
| Solubility | Soluble in DMSO ≥2mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28144730 |
| SMILES | CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F.Cl |
| InChIKey | RCHQNUQAHJNRBY-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H21F3N8O3S.ClH/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21，22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3，33)34;/h4-10H，11H2，1-3H3，(H，24，32)(H2，27，28，29，30);1H |
| PubChem CID | 25117347 |
| Target Point | FAK |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor， which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.[1] |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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