Chinese Name |
蛋白磷酸酶2调节亚单位A亚型α |
Target |
PPP2R1A |
Synonym |
2AAA_HUMAN; 6330556D22Rik; Alpha isoform of regulatory subunit A, protein phosphatase; DKFZp470L0914; Medium tumor antigen-associated 61 kDa protein; MGC128399; MGC786; MGC83000; MGC95083; PP2A Aalpha; PP2A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; PP2A, subunit A, PR65-alpha isoform; PP2A, subunit A, R1-alpha isoform; PP2AAALPHA; Ppp2r1a; ppp2r1a-b; PR65; PR65-alpha; PR65A; Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), alpha isoform, isoform CRA_a; Protein phosphatase 2 (formerly 2A), regulatory subunit A,; Protein phosphatase 2 regulatory subunit A alpha; Protein phosphatase 2, 65-KD regulatory subunit A, alpha; Protein phosphatase 2, regulatory subunit A, alpha isoform; Protein phosphatase 2, structural/regulatory subunit A, alpha; PPP2R1A; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; |
Backgroud |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. |
Swiss Prot |
P30153 |
Gene ID |
5518 |
Subcellular Localization |
Secreted Cell membrane Nucleus |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Predicted Cross-Reactivity |
Bovine;Pig |
Protein MW |
65kDa |
Observed MW |
65kDa |
Dilution Ratio |
WB 1:1000-3000. IHC 1:50-200. IF 1:50-200. |
Immunogen |
Recombinant protein of human PPP2R1A |
Public Immunogen Range |
1-350aa |
Purification Method |
Octanoic acid-ammonium sulfate precipitation |
Storage Buffer |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human;Mouse;Rat |
Application |
WB;IHC IF |
Specification |
50ul 100ul |