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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Angiogenesis > Tas0728CAS：2088323-16-2
Molecular Formula：C26H32N8O3
Molecular Weight：504.6
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 2088323-16-2 |
| Name | Tas0728 |
| Molecular Formula | C26H32N8O3 |
| Molecular Weight | 504.6 |
| Solubility | Soluble in DMSO ≥10mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD31813813 |
| SMILES | CC1=C(C=CC(=C1C)NC(=O)C2=NN(C3=NC=NC(=C23)N)[C@@H]4CCCN(C4)C(=O)C=C)CC(=O)N(C)C |
| InChIKey | JCCIICHPRAAMGK-GOSISDBHSA-N |
| InChI | InChI=1S/C26H32N8O3/c1-6-20(35)33-11-7-8-18(13-33)34-25-22(24(27)28-14-29-25)23(31-34)26(37)30-19-10-9-17(15(2)16(19)3)12-21(36)32(4)5/h6，9-10，14，18H，1，7-8，11-13H2，2-5H3，(H，30，37)(H2，27，28，29)/t18-/m1/s1 |
| PubChem CID | 130275856 |
| Target Point | HER2 |
| Passage | Angiogenesis; Protein Tyrosine Kinase/RTK |
| Background | TAS0728 is a potent, selective, irreversible and covalently bound HER2 inhibitor, which covalently binds to the C805 site of HER2 and inhibits its activity. TAS0728 also inhibited the phosphorylation of HER2, HER3 and their downstream effector proteins. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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