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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > GK-921CAS：1025015-40-0
Molecular Formula：C21H20N4O
Molecular Weight：344.41
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Off-white to brown Solid
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| CAS | 1025015-40-0 |
| Name | GK-921 |
| Molecular Formula | C21H20N4O |
| Molecular Weight | 344.41 |
| Solubility | Soluble in DMSO ≥3mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | Off-white to brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD28167818 |
| SMILES | C1CCN(C1)CCOC2=NC3=C(N=CC=C3)N=C2C#CC4=CC=CC=C4 |
| InChIKey | MNYJJHBAEYKXEG-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H20N4O/c1-2-7-17(8-3-1)10-11-19-21(26-16-15-25-13-4-5-14-25)24-18-9-6-12-22-20(18)23-19/h1-3，6-9，12H，4-5，13-16H2 |
| PubChem CID | 56682080 |
| Target Point | Transglutaminase 2 (TGase 2) |
| Passage | Metabolic Enzyme&Protease |
| Background | GK-921 is a transglutaminase 2 (TGase 2) inhibitor. |
| Biological Activity | GK921 is a transglutaminase 2 (TGase) inhibitor with an IC50 of 7.71 μM for human recombinant TGase 2.[1] |
| IC50 | IC50: 7.71 μM (TGase)[1] |
| Data Literature Source | [1]. Ku BM， et al. Transglutaminase 2 inhibitor abrogates renal cell carcinoma in xenograft models. J Cancer Res Clin Oncol. 2014 May;140(5):757-67. |
| Unit | Bottle |
| Specification | 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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