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Lipopolysaccharides(LPS)
Appearance:Lyophilized powder
Storage:Store at 2-8℃
Akkermansia muciniphila (A. muciniphila) is A gram-negative, anaerobic, non-motile, non-spore-forming and oval-shaped bacterium. LPS from A. muciniphila stimulates the production of NF-κB-dependent embryonic cell alkaline phosphatase (SEAP) through TLR4. In addition, it induces IL-8, IL-6 and very small amounts of IL-10 and TNF-α in peripheral blood mononuclear cells (PBMC). A. muciniphila stimulation of intestinal cells to produce IL-8 was shown to be significantly lower (100 times) than E. coli stimulation. Low pro-inflammatory activity keeps the mucosal associated immune system at an appropriate level to produce mucosal homeostasis.
Remark：
These protocols are for reference only. Solarbio does not independently validate these
methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
