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Appearance:White to light yellow powder
Storage:Store at 2-8℃
Lipopolysaccharide is a type of sugar lipid that consists of carbohydrates linked to fatty acids. It is a characteristic component of the cell wall of Gram-negative bacteria. The typical LPS molecule has lipid A (a phospholipid based on glucosamine), a relatively short core oligosaccharide, and a distal polysaccharide (O-antigen). LPS contributes to the integrity of the outer membrane and can protect cells from bile salts and lipophilic antibiotics. They stimulate host cells via TLR2 and TLR4 (toll-like receptors). This stimulation can lead to the production of various pro-inflammatory cytokines, such as TNF-α (tumor necrosis factor), IL-1 (interleukin-1), and IL-6. The product is extracted by phenol from E. coli serotype O111:B4. This LPS serotype has been used to stimulate B cells and induce NOS in human hepatocytes.
