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My CartReactivity：Mouse,Rat,Human
Application：WB,IHC,IF
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：26408
Host：Rabbit
Qty：
Size：
| Name | Anti-ASK1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-1000.IHC 1:500-1000.IF 1:500-1000. |
| Target | ASK1 |
| Background | Apoptosis signal regulated kinase 1 (ASK1) is a widely expressed redox sensitive serine/threonine kinase, composed of the N-terminal TRX binding domain (ASK1-TBD), the central regulatory region containing the TRAF binding domain (ASK1-CRR), and the serine/threonine kinase domain (ASK1-CD), as well as the C-terminal coiled coil (CC) region. ASK1 plays an important role in the cellular response cascade caused by environmental changes, regulating cell apoptosis signal transduction by activating mitochondrial dependent cysteine proteases. It also mediates signal transduction that determines cell fate, such as differentiation and survival. MAP3K5/ASK1 is also necessary for the innate immune response, which is crucial for the host to resist multiple pathogens. |
| Swiss Prot | O35099 |
| Gene ID | 26408 |
| Subcellular Location | Cytoplasm |
| Immunogen | Recombinant protein of mouse ASK1 |
| Calculated MW | 155kDa |
| Observed MW | 155kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 100ul |
| Reactivity | Mouse Rat Human |
| Application | IHC IF WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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