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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cell Cycle > UnesbulinCAS：1610964-64-1
Molecular Formula：C19H13F5N6
Molecular Weight：420.34
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1610964-64-1 |
| Name | Unesbulin |
| Molecular Formula | C19H13F5N6 |
| Molecular Weight | 420.34 |
| Solubility | Soluble in DMSO ≥1mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | CC1=NC2=C(N1C3=NC(=C(C(=N3)NC4=CC=C(C=C4)C(F)(F)F)F)N)C=C(C=C2)F |
| InChIKey | TWLWOOPCEXYVBE-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H13F5N6/c1-9-26-13-7-4-11(20)8-14(13)30(9)18-28-16(25)15(21)17(29-18)27-12-5-2-10(3-6-12)19(22，23)24/h2-8H，1H3，(H3，25，27，28，29) |
| PubChem CID | 74223469 |
| Target Point | BMI-1 |
| Passage | Cell Cycle;DNA Damage/DNA Repair |
| Background | Unesbulin is a selective B-cell-specific inhibitor of Moloney's murine leukemia virus integration site-1 (BMI-1). Bulin Unesbulin can down-regulate MCL-1 and induce mitochondrial apoptosis independent of p53 in acute myeloid leukemia cells, and it can be used as a related research in the treatment of leukemia. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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