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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > PI3K/Akt/mTOR > Vacuolin-1CAS：351986-85-1
Molecular Formula：C26H24IN7O
Molecular Weight：577.43
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 351986-85-1 |
| Name | Vacuolin-1 |
| Molecular Formula | C26H24IN7O |
| Molecular Weight | 577.43 |
| Solubility | Soluble in DMSO ≥1mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 636-870-9 |
| SMILES | C1COCCN1C2=NC(=NC(=N2)NN=CC3=CC(=CC=C3)I)N(C4=CC=CC=C4)C5=CC=CC=C5 |
| InChIKey | JMEJTSRAQUFNOP-TURZUDJPSA-N |
| InChI | InChI=1S/C26H24IN7O/c27-21-9-7-8-20(18-21)19-28-32-24-29-25(33-14-16-35-17-15-33)31-26(30-24)34(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-13，18-19H，14-17H2，(H，29，30，31，32)/b28-19+ |
| PubChem CID | 9661141 |
| Target Point | PIKfyve |
| Passage | PI3K/Akt/mTOR |
| Background | Vacuolin-1 is a potent and selective PIKfyve inhibitor that inhibits late autophagy by impairs lysosomal maturation. Vacuolin-1 is also a potent lysosomal exocytosis inhibitor, blocking lysosomal Ca2+ dependent exocytosis and preventing the release of lysosomal contents without affecting the resealing process. |
| Unit | Bottle |
| Specification | 1mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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