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Rapamycin
CAS:53123-88-9
Appearance:White Powder
Storage:Store at -20℃，avoid light and moisture，keep seal，3 years.
Purity:98.00%
Product Description
Macrocyclic-triene antibiotic possessing potent immunosuppressant activity. It forms a complex with FKBP12?that binds to an effector, thus inhibiting IL-2 and other growth promoting lymphokines. The effectors were?recently identified as FRAP (FKBP12 rapamycin-associated protein) and RAFT1 (rapamycin and KFBP12target). Rapamycin induces inhibition of p70s6k, p33cdk2 and p34cdc2. Enhances apoptosis.SOURCE/HOST: Isolated from Streptomyces hygroscopicus.
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These protocols are for reference only. Solarbio does not independently validate these
methods.
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用于动物实验怎么溶解2022-07-07 18:07:49
Administrator雷帕霉素用DMSO溶解；DMSO本身有毒性，不同动物对DMSO的耐受不同（一般建议DMSO小于千分之一），建议根据文献摸索一下DMSO用量