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My Cart> Antibodies > Loading Control Antibodies > Plasmalemma > Anti-E-Cadherin Polyclonal AntibodyReactivity：Human,Mouse
Application：IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：999
Host：Rabbit
Qty：
Size：
| Name | Anti-E-Cadherin Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-2000.IHC 1:50-200. |
| Target | E-Cadherin |
| Background | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants，at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats，a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric，breast，colorectal，thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation，invasion，and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. |
| Swiss Prot | P12830 |
| Gene ID | 999 |
| Subcellular Location | Cell junction，Cell membrane，Endosome，Golgi apparatus，Single-pass type I membrane protein，trans-Golgi network |
| Immunogen | Recombinant protein of human E-Cadherin |
| Public Immunogen Range | 373-622aa |
| Calculated MW | 97kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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