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My CartReactivity：Mouse,Rat,Human
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：53905
Host：Rabbit
Qty：
Size：
| Name | Anti-DUOX1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Pig |
| Dilution Ratio | WB 1:1000-3000.IHC 1:100-300. |
| Target | DUOX1 |
| Background | The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter，thyroperoxidase，and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase，lactoperoxidase，and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. |
| Swiss Prot | Q9NRD9 |
| Gene ID | 53905 |
| Subcellular Location | Cytoplasm Cell membrane |
| Immunogen | Recombinant protein of human DUOX1 |
| Public Immunogen Range | 20-370aa |
| Calculated MW | 138/177kDa |
| Observed MW | 165kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Rat Mouse |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with DUOX1 antibody diluted at 1:2000;Lane: Mouse liver,Rat liver.
Immunohistochemistry of paraffin-embedded Human testis cancer with DUOX1 antibody diluted at 1:200.
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