{{cart_num}}
My CartReactivity：Human
Application：FCM
Clone Type：Monoclonal Antibody
Storage：Store at 4℃ in dark.Do not freeze.
Gene ID：4907
Host：Mouse
Qty：
Size：
| Name | Anti-CD73(PE) Monoclonal Antibody |
| Host | Mouse |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG1，κ |
| Dilution Ratio | FCM 5uL/Test. |
| Target | CD73 |
| Background | CD73 is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins，CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants，yet elicits diverse biological function through differential regulation in endothelial cells (EC)，subpopulations of B and T cells，germinal center follicular dendritic cells and on thymic medullary reticular fibroblasts. For example，IgG mediated neutralization of CD73 interferes with lymphocyte adhesion to EC，and blocks aggregation of germinal center B cells and follicular dendritic cells. Furthermore，IgG-mediated targeting of lymphocyte CD73，but not of endothelial cell CD73，causes shedding of CD73 and tyrosine phosphorylation of proteins. |
| Swiss Prot | P21589 |
| Gene ID | 4907 |
| Subcellular Location | Cell membrane |
| Storage | Store at 4℃ in dark.Do not freeze. |
| Unit | Piece |
| Specification | 25T 100T |
| Reactivity | Human |
| Application | FCM |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no experimental images.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
