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My Cart> Antibodies > Loading Control Antibodies > Plasmalemma > Anti-CD71 Monoclonal AntibodyReactivity：Human
Application：FCM
Clone Type：Monoclonal Antibody
Storage：Store at 4℃ in dark.Do not freeze.
Gene ID：7037
Host：Mouse
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| Name | Anti-CD71 Monoclonal Antibody |
| Host | Mouse |
| Clone Type | Monoclonal Antibody |
| Subtype | IgG1 |
| Target | CD71 |
| Background | Cellular uptake of iron occurs via receptor mediated endocytosis of ligand occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Useful in studies of dividing haematopoietic and tumour cell populations，and metabolic activity. A second ligand，the heditary hemochromatosis protein HFE，competes for binding with transferrin for an overlapping C terminal binding site. The antigen is present on most dividing cells，including normally cycling in vivo hematopoietic progenitor cells，mitogenically stimulated cells in vitro，some primary tumor cells and most proliferating cells in vitro. |
| Swiss Prot | P02786 |
| Gene ID | 7037 |
| Subcellular Location | Cell membrane |
| Storage | Store at 4℃ in dark.Do not freeze. |
| Unit | Piece |
| Specification | 100ug 1mg |
| Reactivity | Human |
| Application | FCM |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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