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Your Position: Home > Molecular Biology > Nucleic Acid Extraction/Purification > mRNA Capping Rate Pretreatment Kit
mRNA Capping Rate Pretreatment Kit

Storage:Storage mreagent, 10xM buffer and Buffer1 at -20℃, the remaining ingredients at 4℃. Do not freeze or thaw magnetic beads.

mRNA Capping Rate Pretreatment Kit
Cat.No：
R8590
Brand：
Solarbio
SKU Tongzhou Beijing Haidian Beijing Wuhan Guangzhou
R8590-10T Inquiry Inquiry Inquiry Inquiry
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Product Information Related Products Related Paper COA Technical Q&A

Capping rate is an important quality attribute index of mRNA vaccine drugs and a necessary validation data for the application of mRNA products. At present, the determination of cap rate is mainly carried out by LMS. There are hundreds of orders of magnitude difference in molecular weight between capped mRNA and uncapped mRNA, and it is difficult to accurately analyze the difference between capped and uncapped samples compared to the hundreds of thousands of molecular weight of intact mRNA. Therefore, analysis of the capping rate first requires processing long fragments of mRNA into small fragments, turning differences of the order of hundreds of thousands into differences of the order of thousands. The pre-treatment kit for mRNA capping rate detection provided by Solarbio can accurately and efficiently process mRNA samples, and the treated samples can be directly used for LMS analysis, helping to quickly analyze the sample capping rate. This kit is suitable for pretreatment of mRNA samples with different capping methods and various cap structures

Remark：
These protocols are for reference only. Solarbio does not independently validate these methods.

Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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