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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：80380
Application：Blocking Peptide of K114785P Antibody
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| Name | PDCD1LG2 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | Q9BQ51 |
| Gene ID | 80380 |
| Background | Programmed Death Ligand 2 (PD-L2); also known as B7-DC and butyrophilin-like protein; is a member of the B7 family of proteins that provide signals for regulating T-cell activation and tolerance .PD-L2 is expressed on dendritic cells; subsets of activated CD4+ and CD8+ T cells; and memory B cells that differentiate into plasma cells. At inflammatory sites such as rheumatoid arthritis; allergen exposure; and virus infection; PD-L2 is up-regulated on synoviocytes; infiltrating macrophages; dendritic cells; and airway epithelial cells. PD-L2; along with B7-H1/PD-L1; binds to T cell PD-1 where it promotes IFN-gamma production and CD40 Ligand up-regulation while inhibiting IL-4 production. In addition; PD-L2 binds to RGM-B on macrophages and alveolar epithelial cells; supporting respiratory immune tolerance. In asthma; PD-L2 suppresses IL-5 and IL-13 production; promotes IL-12 production by dendritic cells; and supports allergen-induced airway hyper-responsiveness and mucus production. |
| Application | Blocking Peptide of K114785P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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