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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：5571
Application：Blocking Peptide of K108070P Antibody
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| Name | PRKAG1 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | P54619 |
| Gene ID | 5571 |
| Background | AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK)， an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels， AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein， carbohydrate and lipid biosynthesis， as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes， and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP， ADP and ATP， leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation， without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit， rendering the AMPK enzyme inactive. |
| Application | Blocking Peptide of K108070P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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