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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：54386
Application：Blocking Peptide of K108266P Antibody
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| Name | TERF2IP Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | Q9NYB0 |
| Gene ID | 54386 |
| Background | Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex; it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead; it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR); which can affect telomere length. Does not bind DNA directly: recruited to telomeric double-stranded 5’-TTAGGG-3’ repeats via its interaction with TERF2. Independently of its function in telomeres; also acts as a transcription regulator: recruited to extratelomeric 5’-TTAGGG-3’ sites via its association with TERF2 or other factors; and regulates gene expression. When cytoplasmic; associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65; leading to activate expression of NF-kappa-B target genes. |
| Application | Blocking Peptide of K108266P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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