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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：253430
Application：Blocking Peptide of K108675P Antibody
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| Name | IPMK Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | Q8NFU5 |
| Gene ID | 253430 |
| Background | Inositol phosphate kinase with a broad substrate specificity. Phosphorylates inositol 1，4，5-trisphosphate (Ins(1，4，5)P3) first to inositol 1，3，4，5-tetrakisphosphate and then to inositol 1，3，4，5，6-pentakisphosphate (Ins(1，3，4，5，6)P5). Phosphorylates inositol 1，3，4，6-tetrakisphosphate (Ins(1，3，4，6)P4). Phosphorylates glycero-3-phospho-1D-myo-inositol 4，5-bisphosphate to glycero-3-phospho-1D-myo-inositol 3，4，5-trisphosphate. Plays an important role in MLKL-mediated necroptosis via its role in the biosynthesis of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Binding of these highly phosphorylated inositol phosphates to MLKL mediates the release of an N-terminal auto-inhibitory region， leading to activation of the kinase. Essential for activated phospho-MLKL to oligomerize and localize to the cell membrane during necroptosis. Required for normal embryonic development， probably via its role in the biosynthesis of inositol 1，3，4，5，6-pentakisphosphate (Ins(1，3，4，5，6)P5) and inositol hexakisphosphate (InsP6). |
| Application | Blocking Peptide of K108675P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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